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Acute glucose fluctuation promotes RAGE expression via reactive oxygen species-mediated NF-κB activation in rat podocytes

Diabetic nephropathy (DN) is a common chronic complication of diabetes, for which acute glucose fluctuation (AGF) is a potential risk factor. Fluctuating hyperglycemia has been confirmed to induce more serious kidney damage than hyperglycemia in diabetic rats; however, the mechanism remains unknown....

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Detalles Bibliográficos
Autores principales: Hu, Zhangjie, Fang, Wenming, Liu, Yi, Liang, Haowei, Chen, Wei, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974412/
https://www.ncbi.nlm.nih.gov/pubmed/33760170
http://dx.doi.org/10.3892/mmr.2021.11969

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