Cargando…

Inhibition of chaperone-mediated autophagy reduces tumor growth and metastasis and promotes drug sensitivity in colorectal cancer

Chaperone-mediated autophagy (CMA) is a selective type of autophagy whereby a specific subset of intracellular proteins is targeted to the lysosome for degradation. The present study investigated the mechanisms underlying the response and resistance to 5-fluorouracil (5-FU) in colorectal cancer (CRC...

Descripción completa

Detalles Bibliográficos
Autores principales: Xuan, Ying, Zhao, Shuang, Xiao, Xingjun, Xiang, Liwei, Zheng, Hua-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974415/
https://www.ncbi.nlm.nih.gov/pubmed/33760140
http://dx.doi.org/10.3892/mmr.2021.11999

Ejemplares similares