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Protein/AS01(B) vaccination elicits stronger, more Th2-skewed antigen-specific human T follicular helper cell responses than heterologous viral vectors

Interactions between B cells and CD4(+) T follicular helper (Tfh) cells are key determinants of humoral responses. Using samples from clinical trials performed with the malaria vaccine candidate antigen Plasmodium falciparum merozoite protein (PfRH5), we compare the frequency, phenotype, and gene ex...

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Detalles Bibliográficos
Autores principales:	Nielsen, Carolyn M., Ogbe, Ane, Pedroza-Pacheco, Isabela, Doeleman, Susanne E., Chen, Yue, Silk, Sarah E., Barrett, Jordan R., Elias, Sean C., Miura, Kazutoyo, Diouf, Ababacar, Bardelli, Martino, Dabbs, Rebecca A., Barfod, Lea, Long, Carole A., Haynes, Barton F., Payne, Ruth O., Minassian, Angela M., Bradley, Todd, Draper, Simon J., Borrow, Persephone
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974546/ https://www.ncbi.nlm.nih.gov/pubmed/33763653 http://dx.doi.org/10.1016/j.xcrm.2021.100207

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