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Use of Ultrasmall Core-Shell Fluorescent Silica Nanoparticles for Image-Guided Sentinel Lymph Node Biopsy in Head and Neck Melanoma: A Nonrandomized Clinical Trial

IMPORTANCE: Sentinel lymph node (SLN) mapping agents approved for current surgical practice lack sufficient brightness and target specificity for high-contrast, sensitive nodal visualization. OBJECTIVE: To evaluate whether an ultrasmall, molecularly targeted core-shell silica nanoparticle (Cornell p...

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Detalles Bibliográficos
Autores principales: Zanoni, Daniella Karassawa, Stambuk, Hilda E., Madajewski, Brian, Montero, Pablo H., Matsuura, Danielli, Busam, Klaus J., Ma, Kai, Turker, Melik Z., Sequeira, Sonia, Gonen, Mithat, Zanzonico, Pat, Wiesner, Ulrich, Bradbury, Michelle S., Patel, Snehal G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974643/
https://www.ncbi.nlm.nih.gov/pubmed/33734415
http://dx.doi.org/10.1001/jamanetworkopen.2021.1936