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Use of Ultrasmall Core-Shell Fluorescent Silica Nanoparticles for Image-Guided Sentinel Lymph Node Biopsy in Head and Neck Melanoma: A Nonrandomized Clinical Trial
IMPORTANCE: Sentinel lymph node (SLN) mapping agents approved for current surgical practice lack sufficient brightness and target specificity for high-contrast, sensitive nodal visualization. OBJECTIVE: To evaluate whether an ultrasmall, molecularly targeted core-shell silica nanoparticle (Cornell p...
Autores principales: | Zanoni, Daniella Karassawa, Stambuk, Hilda E., Madajewski, Brian, Montero, Pablo H., Matsuura, Danielli, Busam, Klaus J., Ma, Kai, Turker, Melik Z., Sequeira, Sonia, Gonen, Mithat, Zanzonico, Pat, Wiesner, Ulrich, Bradbury, Michelle S., Patel, Snehal G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Medical Association
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974643/ https://www.ncbi.nlm.nih.gov/pubmed/33734415 http://dx.doi.org/10.1001/jamanetworkopen.2021.1936 |
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