Identification of tumor mutation burden-related hub genes and the underlying mechanism in melanoma

Background: Tumor mutation burden (TMB) has emerged as an important predictive factor for drug resistance in cancers; however, the specific mechanism underlying TMB function in melanoma remains elusive. Methods: Data on somatic mutations, RNA sequencing (RNA-seq), miRNA sequencing (miRNA-seq), and c...

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Detalles Bibliográficos
Autores principales: Zhang, Chuan, Dang, Dan, Liu, Chenlu, Wang, Yuqian, Cong, Xianling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7974884/
https://www.ncbi.nlm.nih.gov/pubmed/33758620
http://dx.doi.org/10.7150/jca.53697

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