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Intra-arterial infusion of autologous bone marrow mononuclear cells combined with intravenous injection of cerebrolysin in the treatment of middle cerebral artery ischemic stroke: Case report
We present a patient with severe middle cerebral artery occlusion who received an intra-arterial infusion of autologous bone marrow stem cells combined with Cerebrolysin IV. The patient was evaluated before and after treatment using the National Institutes of Health Stroke Scale, the Medical Researc...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975445/ https://www.ncbi.nlm.nih.gov/pubmed/33796315 http://dx.doi.org/10.1177/2050313X211002313 |
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author | Le, Vien C Nguyen, Ngoc H Le, Song H |
author_facet | Le, Vien C Nguyen, Ngoc H Le, Song H |
author_sort | Le, Vien C |
collection | PubMed |
description | We present a patient with severe middle cerebral artery occlusion who received an intra-arterial infusion of autologous bone marrow stem cells combined with Cerebrolysin IV. The patient was evaluated before and after treatment using the National Institutes of Health Stroke Scale, the Medical Research Council Muscle Scale, Modified Brunnstrom Classification, Barthel Index and modified Rankin Scale. After the therapy, the patient showed good outcome with functional as well as neurological improvements especially in terms of functional motor recovery without any side effects. Further controlled studies are needed to find possible side effects and establish net efficacy. |
format | Online Article Text |
id | pubmed-7975445 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-79754452021-03-31 Intra-arterial infusion of autologous bone marrow mononuclear cells combined with intravenous injection of cerebrolysin in the treatment of middle cerebral artery ischemic stroke: Case report Le, Vien C Nguyen, Ngoc H Le, Song H SAGE Open Med Case Rep Case Report We present a patient with severe middle cerebral artery occlusion who received an intra-arterial infusion of autologous bone marrow stem cells combined with Cerebrolysin IV. The patient was evaluated before and after treatment using the National Institutes of Health Stroke Scale, the Medical Research Council Muscle Scale, Modified Brunnstrom Classification, Barthel Index and modified Rankin Scale. After the therapy, the patient showed good outcome with functional as well as neurological improvements especially in terms of functional motor recovery without any side effects. Further controlled studies are needed to find possible side effects and establish net efficacy. SAGE Publications 2021-03-17 /pmc/articles/PMC7975445/ /pubmed/33796315 http://dx.doi.org/10.1177/2050313X211002313 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Case Report Le, Vien C Nguyen, Ngoc H Le, Song H Intra-arterial infusion of autologous bone marrow mononuclear cells combined with intravenous injection of cerebrolysin in the treatment of middle cerebral artery ischemic stroke: Case report |
title | Intra-arterial infusion of autologous bone marrow mononuclear cells
combined with intravenous injection of cerebrolysin in the treatment of middle
cerebral artery ischemic stroke: Case report |
title_full | Intra-arterial infusion of autologous bone marrow mononuclear cells
combined with intravenous injection of cerebrolysin in the treatment of middle
cerebral artery ischemic stroke: Case report |
title_fullStr | Intra-arterial infusion of autologous bone marrow mononuclear cells
combined with intravenous injection of cerebrolysin in the treatment of middle
cerebral artery ischemic stroke: Case report |
title_full_unstemmed | Intra-arterial infusion of autologous bone marrow mononuclear cells
combined with intravenous injection of cerebrolysin in the treatment of middle
cerebral artery ischemic stroke: Case report |
title_short | Intra-arterial infusion of autologous bone marrow mononuclear cells
combined with intravenous injection of cerebrolysin in the treatment of middle
cerebral artery ischemic stroke: Case report |
title_sort | intra-arterial infusion of autologous bone marrow mononuclear cells
combined with intravenous injection of cerebrolysin in the treatment of middle
cerebral artery ischemic stroke: case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975445/ https://www.ncbi.nlm.nih.gov/pubmed/33796315 http://dx.doi.org/10.1177/2050313X211002313 |
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