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Bovine serum albumin aggravates macrophage M1 activation and kidney injury in heterozygous Klotho-deficient mice via the gut microbiota-immune axis

Klotho expression abnormalities induces kidney injury and chronic kidney disease, however, the underlying mechanism remains unclear. Here, Klotho(+/-) mice and wild-type mice were treated with low-dose bovine serum albumin (BSA). Pathological examination demonstrated that the area of glomerular coll...

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Detalles Bibliográficos
Autores principales: Lai, Lingyun, Li, Yi, Liu, Jianjun, Luo, Lei, Tang, Jianguo, Xue, Jun, Liu, Te
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975693/
https://www.ncbi.nlm.nih.gov/pubmed/33767585
http://dx.doi.org/10.7150/ijbs.56424

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