Cargando…

AKR1B10 confers resistance to radiotherapy via FFA/TLR4/NF-κB axis in nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is one kind of human head and neck cancers with high incidence in Southern China, Southeast Asia and North Africa. In spite of great innovations in radiation and chemotherapy treatments, the 5-year survival rate is not satisfactory. One of the main reasons is resistanc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Xiangting, Hu, Zheng, Qu, Jiayao, Li, Jia, Gong, Ke, Wang, Li, Jiang, Jing, Li, Xiangning, He, Rongzhang, Duan, Lili, Luo, Weihao, Xia, Chenglai, Luo, Dixian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975703/ https://www.ncbi.nlm.nih.gov/pubmed/33767586 http://dx.doi.org/10.7150/ijbs.52927

Ejemplares similares

AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway
por: Qu, Jiayao, et al.
Publicado: (2021)

AKR1B10 promotes breast cancer cell migration and invasion via activation of ERK signaling
por: Li, Jia, et al.
Publicado: (2017)

Aldo-Keto Reductase Family 1 Member B10 Inhibitors: Potential Drugs for Cancer Treatment
por: Huang, Li, et al.
Publicado: (2016)

Cas9 Mediated Correction of β-catenin Mutation and Restoring the Expression of Protein Phosphorylation in Colon Cancer HCT-116 Cells Decrease Cell Proliferation in vitro and Hamper Tumor Growth in Mice in vivo
por: Li, Yanlan, et al.
Publicado: (2020)

A novel long non-coding RNA-KAT7 is low expressed in colorectal cancer and acts as a tumor suppressor
por: Wang, Qingmei, et al.
Publicado: (2019)

Low expression of Aldo–keto reductase 1B10 is a novel independent prognostic indicator for nasopharyngeal carcinoma
por: Guo, Yuanwei, et al.
Publicado: (2016)

The role of long non-coding RNAs in nasopharyngeal carcinoma: As systemic review
por: He, Rongzhang, et al.
Publicado: (2016)

The Effect and Mechanism of TLR9/KLF4 in FFA-Induced Adipocyte Inflammation
por: Wang, Cuizhe, et al.
Publicado: (2018)

Feprazone Prevents Free Fatty Acid (FFA)-Induced Endothelial Inflammation by Mitigating the Activation of the TLR4/MyD88/NF-κB Pathway
por: Song, Min, et al.
Publicado: (2021)

Expression of the Aldo-Ketoreductases AKR1B1 and AKR1B10 in Human Cancers
por: Laffin, Brian, et al.
Publicado: (2012)

AKR1B1 and AKR1B10 as Prognostic Biomarkers of Endometrioid Endometrial Carcinomas
por: Hojnik, Marko, et al.
Publicado: (2021)

Enzymes of the AKR1B and AKR1C Subfamilies and Uterine Diseases
por: Rižner, Tea Lanišnik
Publicado: (2012)

Triptolide Combined with Radiotherapy for the Treatment of Nasopharyngeal Carcinoma via NF-κB-Related Mechanism
por: Zhang, Weiying, et al.
Publicado: (2016)

Label-free cell phenotypic study of FFA4 and FFA1 and discovery of novel agonists of FFA4 from natural products
por: Xu, Fangfang, et al.
Publicado: (2019)

AKR1B10 in gastrointestinal diseases
por: Shen, Yi, et al.
Publicado: (2015)

In-silico Investigations of quinine and quinidine as potential Inhibitors of AKR1B1 and AKR1B10: Functional and structural characterization
por: Ejaz, Syeda Abida, et al.
Publicado: (2022)

Nephropathogenic Infectious Bronchitis Virus Mediates Kidney Injury in Chickens via the TLR7/NF-κB Signaling Axis
por: Li, Ning, et al.
Publicado: (2022)

The Role of AKR1B10 in Physiology and Pathophysiology
por: Endo, Satoshi, et al.
Publicado: (2021)

Selective Orthosteric Free Fatty Acid Receptor 2 (FFA2) Agonists: IDENTIFICATION OF THE STRUCTURAL AND CHEMICAL REQUIREMENTS FOR SELECTIVE ACTIVATION OF FFA2 VERSUS FFA3
por: Schmidt, Johannes, et al.
Publicado: (2011)

Biochanin A attenuates myocardial ischemia/reperfusion injury through the TLR4/NF-κB/NLRP3 signaling pathway
por: Bai, Yejun, et al.
Publicado: (2019)

Resistin Promotes Nasopharyngeal Carcinoma Metastasis through TLR4-Mediated Activation of p38 MAPK/NF-κB Signaling Pathway
por: Zhang, Zongmeng, et al.
Publicado: (2022)

Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner
por: Xie, Mengru, et al.
Publicado: (2020)

Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma
por: Zhou, Jiahui, et al.
Publicado: (2016)

Retraction: Trop2 promotes proliferation, invasion and EMT of nasopharyngeal carcinoma cells through the NF-κB pathway
por: Cheng, Nan, et al.
Publicado: (2022)

Long Chain Fatty Acids as Modulators of Immune Cells Function: Contribution of FFA1 and FFA4 Receptors
por: Hidalgo, Maria A., et al.
Publicado: (2021)

OR23-4 Intestinal FFA2 and FFA3 Mediate Obesogenic Effects in Mice on a Western Diet
por: Gough, Sophie, et al.
Publicado: (2022)

In vitro and in vivo evaluation of T and B lymphocyte functions in AKR mice.
por: Collavo, D., et al.
Publicado: (1975)

Dihydromyricetin Attenuates Inflammation through TLR4/NF-kappaB Pathway
por: Jing, Nianshui, et al.
Publicado: (2019)

Distinct response properties between the FFA to faces and the PPA to houses
por: Li, Mengjin, et al.
Publicado: (2022)

TLR9 signaling activation at different stages in colorectal cancer and NF-kappaB expression
por: Gao, Caixia, et al.
Publicado: (2018)

AKR1B10 expression predicts response of gastric cancer to neoadjuvant chemotherapy
por: Ahmed, Syed Minhaj Uddin, et al.
Publicado: (2019)

FFA2 Contribution to Gestational Glucose Tolerance Is Not Disrupted by Antibiotics
por: Fuller, Miles, et al.
Publicado: (2016)

The Role of bFGF in the Excessive Activation of Astrocytes Is Related to the Inhibition of TLR4/NFκB Signals
por: Ye, Libing, et al.
Publicado: (2015)

AKR7A3 suppresses tumorigenicity and chemoresistance in hepatocellular carcinoma through attenuation of ERK, c-Jun and NF-κB signaling pathways
por: Chow, Raymond Kwok Kei, et al.
Publicado: (2016)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

Fusobacterium nucleatum-derived small extracellular vesicles facilitate tumor growth and metastasis via TLR4 in breast cancer
por: Li, Guiqiu, et al.
Publicado: (2023)

Rhodococcus equi-Derived Extracellular Vesicles Promoting Inflammatory Response in Macrophage through TLR2-NF-κB/MAPK Pathways
por: Xu, Zhaokun, et al.
Publicado: (2022)

MicroRNA-19b-3p regulates nasopharyngeal carcinoma radiosensitivity by targeting TNFAIP3/NF-κB axis
por: Huang, Teng, et al.
Publicado: (2016)

Mechanism of Probiotic VSL#3 Inhibiting NF-κB and TNF-α on Colitis through TLR4-NF-κB Signal Pathway
por: WANG, Hui, et al.
Publicado: (2019)

Retraction on “Dihydromyricetin attenuates inflammation through TLR4/NF-kappa B pathway”
por: Jing, Nianshui, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_e60kv9ikio7mcmjs7bj1a60hql