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Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy

BACKGROUND AND AIM: The COVID-19 is an infectious disease caused by the novel coronavirus SARS-CoV-2, declared a public health emergency by the World Health Organization. In this study, we evaluated the seroconversion of SARS-CoV-2 antibodies to find predictors of infection in terms of symptoms, hea...

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Autores principales: De Santi, Mauro, Diotallevi, Aurora, Brandi, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mattioli 1885 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975922/
https://www.ncbi.nlm.nih.gov/pubmed/33682801
http://dx.doi.org/10.23750/abm.v92i1.10847
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author De Santi, Mauro
Diotallevi, Aurora
Brandi, Giorgio
author_facet De Santi, Mauro
Diotallevi, Aurora
Brandi, Giorgio
author_sort De Santi, Mauro
collection PubMed
description BACKGROUND AND AIM: The COVID-19 is an infectious disease caused by the novel coronavirus SARS-CoV-2, declared a public health emergency by the World Health Organization. In this study, we evaluated the seroconversion of SARS-CoV-2 antibodies to find predictors of infection in terms of symptoms, health status, and professions. METHODS: Serological samples of 341 volunteers in a cohort in Marche Region, Italy, were analyzed for the presence of IgM and/or IgG immunoglobulins specific for the SARS-CoV-2. Contextually, an anamnestic questionnaire was administered. The binary logistic regression analysis was used to find the predictors of seroconversion. RESULTS: Forty-nine subjects (14.4 %) were found positive, without significant differences between gender and age groups. The predictors identified inside the variable categories “symptoms,” “risk factors” (smoking habit and established pathologies), and “professions” were the loss of taste and smell (OR, 8.563), cardiovascular diseases (OR, 2.912), and police officers profession (OR, 3.875), respectively. CONCLUSIONS: Although the limited number of subjects recruited in this study, our results could give important findings to be considered for planning preventive strategies in the view of the next COVID-19 waves. (www.actabiomedica.it)
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spelling pubmed-79759222021-03-24 Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy De Santi, Mauro Diotallevi, Aurora Brandi, Giorgio Acta Biomed Original Investigations/Commentaries BACKGROUND AND AIM: The COVID-19 is an infectious disease caused by the novel coronavirus SARS-CoV-2, declared a public health emergency by the World Health Organization. In this study, we evaluated the seroconversion of SARS-CoV-2 antibodies to find predictors of infection in terms of symptoms, health status, and professions. METHODS: Serological samples of 341 volunteers in a cohort in Marche Region, Italy, were analyzed for the presence of IgM and/or IgG immunoglobulins specific for the SARS-CoV-2. Contextually, an anamnestic questionnaire was administered. The binary logistic regression analysis was used to find the predictors of seroconversion. RESULTS: Forty-nine subjects (14.4 %) were found positive, without significant differences between gender and age groups. The predictors identified inside the variable categories “symptoms,” “risk factors” (smoking habit and established pathologies), and “professions” were the loss of taste and smell (OR, 8.563), cardiovascular diseases (OR, 2.912), and police officers profession (OR, 3.875), respectively. CONCLUSIONS: Although the limited number of subjects recruited in this study, our results could give important findings to be considered for planning preventive strategies in the view of the next COVID-19 waves. (www.actabiomedica.it) Mattioli 1885 2021 2021-01-25 /pmc/articles/PMC7975922/ /pubmed/33682801 http://dx.doi.org/10.23750/abm.v92i1.10847 Text en Copyright: © 2020 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License
spellingShingle Original Investigations/Commentaries
De Santi, Mauro
Diotallevi, Aurora
Brandi, Giorgio
Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy
title Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy
title_full Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy
title_fullStr Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy
title_full_unstemmed Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy
title_short Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection in an Italian cohort in Marche Region, Italy
title_sort seroprevalence of severe acute respiratory syndrome coronavirus-2 (sars-cov-2) infection in an italian cohort in marche region, italy
topic Original Investigations/Commentaries
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975922/
https://www.ncbi.nlm.nih.gov/pubmed/33682801
http://dx.doi.org/10.23750/abm.v92i1.10847
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