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Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid?
Food-dependent exercise-induced anaphylaxis (FDEIA) is an IgE-mediated allergy resulting from the combination of the ingestion of an offending food and physical exercise. According literature, oral food challenge (OFC) followed by physical exercise (OFCPE) should be considered the diagnostic gold st...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mattioli 1885
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975926/ https://www.ncbi.nlm.nih.gov/pubmed/33682838 http://dx.doi.org/10.23750/abm.v92i1.10093 |
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author | Miceli Sopo, Stefano Gelsomino, Mariannita Del Vescovo, Ester Bersani, Giulia |
author_facet | Miceli Sopo, Stefano Gelsomino, Mariannita Del Vescovo, Ester Bersani, Giulia |
author_sort | Miceli Sopo, Stefano |
collection | PubMed |
description | Food-dependent exercise-induced anaphylaxis (FDEIA) is an IgE-mediated allergy resulting from the combination of the ingestion of an offending food and physical exercise. According literature, oral food challenge (OFC) followed by physical exercise (OFCPE) should be considered the diagnostic gold standard. In the absence of adverse reactions, other cofactors should be added (e.g. acetylsalicylic acid, alcohol in adulthood), one at a time. But many other factors increase patient’s reactivity. This could reduce the sensitivity of the OFCPE and, consequently, make instructions for patients less reliable. On the other hand, the addition of cofactors not reported by the patient may reduce test specificity. With the help of two exemplary stories, that present opposite outcomes, diagnostic difficulties of FDEIA are discussed. |
format | Online Article Text |
id | pubmed-7975926 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Mattioli 1885 |
record_format | MEDLINE/PubMed |
spelling | pubmed-79759262021-03-24 Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid? Miceli Sopo, Stefano Gelsomino, Mariannita Del Vescovo, Ester Bersani, Giulia Acta Biomed Focus on Food-dependent exercise-induced anaphylaxis (FDEIA) is an IgE-mediated allergy resulting from the combination of the ingestion of an offending food and physical exercise. According literature, oral food challenge (OFC) followed by physical exercise (OFCPE) should be considered the diagnostic gold standard. In the absence of adverse reactions, other cofactors should be added (e.g. acetylsalicylic acid, alcohol in adulthood), one at a time. But many other factors increase patient’s reactivity. This could reduce the sensitivity of the OFCPE and, consequently, make instructions for patients less reliable. On the other hand, the addition of cofactors not reported by the patient may reduce test specificity. With the help of two exemplary stories, that present opposite outcomes, diagnostic difficulties of FDEIA are discussed. Mattioli 1885 2021 2020-12-22 /pmc/articles/PMC7975926/ /pubmed/33682838 http://dx.doi.org/10.23750/abm.v92i1.10093 Text en Copyright: © 2020 ACTA BIO MEDICA SOCIETY OF MEDICINE AND NATURAL SCIENCES OF PARMA http://creativecommons.org/licenses/by-nc-sa/4.0 This work is licensed under a Creative Commons Attribution 4.0 International License |
spellingShingle | Focus on Miceli Sopo, Stefano Gelsomino, Mariannita Del Vescovo, Ester Bersani, Giulia Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid? |
title | Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid? |
title_full | Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid? |
title_fullStr | Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid? |
title_full_unstemmed | Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid? |
title_short | Food Dependent Exercise-Induced Anaphylaxis. Can we trust the oral food challenge with exercise and acetylsalicylic acid? |
title_sort | food dependent exercise-induced anaphylaxis. can we trust the oral food challenge with exercise and acetylsalicylic acid? |
topic | Focus on |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7975926/ https://www.ncbi.nlm.nih.gov/pubmed/33682838 http://dx.doi.org/10.23750/abm.v92i1.10093 |
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