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MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin
miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18–25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic an...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976609/ https://www.ncbi.nlm.nih.gov/pubmed/23815851 http://dx.doi.org/10.1186/2251-6581-12-31 |
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author | Samimi, Hilda Zaki dizaji, Majid Ghadami, Mohsen Shahzadeh fazeli, Abolhasan Khashayar, Patricia Soleimani, Masoud Larijani, Bagher Haghpanah, Vahid |
author_facet | Samimi, Hilda Zaki dizaji, Majid Ghadami, Mohsen Shahzadeh fazeli, Abolhasan Khashayar, Patricia Soleimani, Masoud Larijani, Bagher Haghpanah, Vahid |
author_sort | Samimi, Hilda |
collection | PubMed |
description | miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18–25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic and pathologic cellular processes; They also may act as oncogene or tumor suppressors. Altered expression of a number of microRNAs is reported in process of progression and metastasis of thyroid cancers. Therefore, identification of these microRNAs may shed a light to oncogenesis pathway of thyroid cancers and their metastasis. In addition, microRNAs might apply as potential biological markers in diagnosis and treatment of thyroid cancers. The changes made in miRNAs profile of thyroid cancers are reviewed in this paper. |
format | Online Article Text |
id | pubmed-7976609 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-79766092021-04-12 MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin Samimi, Hilda Zaki dizaji, Majid Ghadami, Mohsen Shahzadeh fazeli, Abolhasan Khashayar, Patricia Soleimani, Masoud Larijani, Bagher Haghpanah, Vahid J Diabetes Metab Disord Review Article miRNAs are non coding ribonucleic acids which are protected with respect to evolution, and have a length of 18–25 nucleotides. microRNAs control the gene expression after transcription, through mRNA destruction or translation processing, and therefore participate in arrangement of the physiologic and pathologic cellular processes; They also may act as oncogene or tumor suppressors. Altered expression of a number of microRNAs is reported in process of progression and metastasis of thyroid cancers. Therefore, identification of these microRNAs may shed a light to oncogenesis pathway of thyroid cancers and their metastasis. In addition, microRNAs might apply as potential biological markers in diagnosis and treatment of thyroid cancers. The changes made in miRNAs profile of thyroid cancers are reviewed in this paper. BioMed Central 2013-07-01 /pmc/articles/PMC7976609/ /pubmed/23815851 http://dx.doi.org/10.1186/2251-6581-12-31 Text en © Samimi et al.; licensee BioMed Central Ltd. 2013 http://creativecommons.org/licenses/by/2.0 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Samimi, Hilda Zaki dizaji, Majid Ghadami, Mohsen Shahzadeh fazeli, Abolhasan Khashayar, Patricia Soleimani, Masoud Larijani, Bagher Haghpanah, Vahid MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin |
title | MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin |
title_full | MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin |
title_fullStr | MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin |
title_full_unstemmed | MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin |
title_short | MicroRNAs networks in thyroid cancers: focus on miRNAs related to the fascin |
title_sort | micrornas networks in thyroid cancers: focus on mirnas related to the fascin |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976609/ https://www.ncbi.nlm.nih.gov/pubmed/23815851 http://dx.doi.org/10.1186/2251-6581-12-31 |
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