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Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instability

BACKGROUND: Genetic variants, underlining phenotypic diversity, are known to distribute unevenly in the human genome. A comprehensive understanding of the distributions of different genetic variants is important for insights into genetic functions and disorders. METHODS: Herein, a sliding-window sca...

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Detalles Bibliográficos
Autores principales: Long, Xi, Xue, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976700/
https://www.ncbi.nlm.nih.gov/pubmed/33741065
http://dx.doi.org/10.1186/s40246-021-00318-3