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Genetic-variant hotspots and hotspot clusters in the human genome facilitating adaptation while increasing instability
BACKGROUND: Genetic variants, underlining phenotypic diversity, are known to distribute unevenly in the human genome. A comprehensive understanding of the distributions of different genetic variants is important for insights into genetic functions and disorders. METHODS: Herein, a sliding-window sca...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7976700/ https://www.ncbi.nlm.nih.gov/pubmed/33741065 http://dx.doi.org/10.1186/s40246-021-00318-3 |