APOL1 variant alleles associate with reduced risk for opportunistic infections in HIV infection

Apolipoprotein L1 (APOL1), an innate immune factor against African trypanosoma brucei, inhibits HIV-1 in vitro. The impact of APOL1 G1-G2 variants on HIV-1-associated opportunistic infections (OIs) is unknown. Here, we report findings from a metaanalysis of four HIV/AIDS prospective cohorts (ALIVE,...

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Detalles Bibliográficos
Autores principales: An, Ping, Sezgin, Efe, Kirk, Gregory D., Duggal, Priya, Binns-Roemer, Elizabeth, Nelson, George, Limou, Sophie, Van Natta, Mark L., Jabs, Douglas A., Estrella, Michelle, Kopp, Jeffrey B., Winkler, Cheryl A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977062/
https://www.ncbi.nlm.nih.gov/pubmed/33674766
http://dx.doi.org/10.1038/s42003-021-01812-z

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