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Polycysteine as a new type of radio-protector ameliorated tissue injury through inhibiting ferroptosis in mice

Amifostine has been the only small molecule radio-protector approved by FDA for decades; however, the serious adverse effects limit its clinical use. To address the toxicity issues and maintain the good potency, a series of modified small polycysteine peptides had been prepared. Among them, compound...

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Detalles Bibliográficos
Autores principales: Zhang, Junling, Li, Kui, Zhang, Qianru, Zhu, Zhimei, Huang, Gongchao, Tian, Hongqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977147/
https://www.ncbi.nlm.nih.gov/pubmed/33602915
http://dx.doi.org/10.1038/s41419-021-03479-0