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Polycysteine as a new type of radio-protector ameliorated tissue injury through inhibiting ferroptosis in mice
Amifostine has been the only small molecule radio-protector approved by FDA for decades; however, the serious adverse effects limit its clinical use. To address the toxicity issues and maintain the good potency, a series of modified small polycysteine peptides had been prepared. Among them, compound...
Autores principales: | Zhang, Junling, Li, Kui, Zhang, Qianru, Zhu, Zhimei, Huang, Gongchao, Tian, Hongqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977147/ https://www.ncbi.nlm.nih.gov/pubmed/33602915 http://dx.doi.org/10.1038/s41419-021-03479-0 |
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