Obesity — A Risk Factor for Psoriasis and COVID-19()

Obesity is a major health problem whose well-known association with psoriasis has been amply described. The importance of obesity as a risk factor for poor prognosis in the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 infection has recently been demon...

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Detalles Bibliográficos
Autores principales: Llamas-Velasco, M., Ovejero-Merino, E., Salgado-Boquete, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AEDV. Published by Elsevier España, S.L.U. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977150/
https://www.ncbi.nlm.nih.gov/pubmed/34629472
http://dx.doi.org/10.1016/j.adengl.2021.03.013
Descripción
Sumario:Obesity is a major health problem whose well-known association with psoriasis has been amply described. The importance of obesity as a risk factor for poor prognosis in the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 infection has recently been demonstrated. This review examines a possible relationship between obesity, psoriasis, and COVID-19, analyzing the pathophysiological links and their practical implications. On the one hand, a higher body mass index increases the risk of psoriasis and is also a factor in metabolic syndrome, which is common in patients with psoriasis and has been implicated in reducing the effectiveness of psoriasis treatments. On the other hand, obesity is a risk factor for severe COVID-19 and mortality. Obesity also promotes a proinflammatory state in the lung, where it compromises respiratory mechanics.

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