Astrocyte-specific hypoxia-inducible factor 1 (HIF-1) does not disrupt the endothelial barrier during hypoxia in vitro

BACKGROUND: Astrocytes (AC) are essential for brain homeostasis. Much data suggests that AC support and protect the vascular endothelium, but increasing evidence indicates that during injury conditions they may lose their supportive role resulting in endothelial cell activation and BBB disturbance....

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Detalles Bibliográficos
Autores principales: Baumann, Julia, Tsao, Chih-Chieh, Huang, Sheng-Fu, Gassmann, Max, Ogunshola, Omolara O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977259/
https://www.ncbi.nlm.nih.gov/pubmed/33736658
http://dx.doi.org/10.1186/s12987-021-00247-2

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