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Tamoxifen suppresses brain metastasis of estrogen receptor-deficient breast cancer by skewing microglia polarization and enhancing their immune functions

BACKGROUND: Brain metastasis of breast cancer exhibits exceedingly poor prognosis, and both triple negative (TN) and Her2(+) subtypes have the highest incidence of brain metastasis. Although estrogen blockers are considered to be ineffective for their treatment, recent evidence indicates that estrog...

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Detalles Bibliográficos
Autores principales:	Wu, Shih-Ying, Sharma, Sambad, Wu, Kerui, Tyagi, Abhishek, Zhao, Dan, Deshpande, Ravindra Pramod, Watabe, Kounosuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977276/ https://www.ncbi.nlm.nih.gov/pubmed/33736709 http://dx.doi.org/10.1186/s13058-021-01412-z

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