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Perspectives on the Genetic Associations of Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a common form of inflammatory spinal arthritis with a complex polygenic aetiology. Genome-wide association studies have identified more than 100 loci, including some involved in antigen presentation (HLA-B27, ERAP1, and ERAP2), some in Th17 responses (IL6R, IL23R, TYK2...

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Detalles Bibliográficos
Autores principales: Wordsworth, B. Paul, Cohen, Carla J., Davidson, Connor, Vecellio, Matteo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977288/
https://www.ncbi.nlm.nih.gov/pubmed/33746951
http://dx.doi.org/10.3389/fimmu.2021.603726