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The role of contraception in preventing HIV-positive births: global estimates and projections
BACKGROUND: Meeting the contraceptive needs of women living with HIV (WLHIV) has primary health benefits for women, in addition to being a key element to prevent mother-to-child HIV transmission. This analysis will estimate the current number of infant HIV infections prevented by contraception in th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977320/ https://www.ncbi.nlm.nih.gov/pubmed/33740919 http://dx.doi.org/10.1186/s12889-021-10570-w |
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author | Sherwood, Jennifer Lankiewicz, Elise Roose-Snyder, Beirne Cooper, Bergen Jones, Austin Honermann, Brian |
author_facet | Sherwood, Jennifer Lankiewicz, Elise Roose-Snyder, Beirne Cooper, Bergen Jones, Austin Honermann, Brian |
author_sort | Sherwood, Jennifer |
collection | PubMed |
description | BACKGROUND: Meeting the contraceptive needs of women living with HIV (WLHIV) has primary health benefits for women, in addition to being a key element to prevent mother-to-child HIV transmission. This analysis will estimate the current number of infant HIV infections prevented by contraception in the era of increased HIV treatment coverage and; 2) model the additional HIV benefits of preventing unintended births to WLHIV. METHODS: Secondary data analysis was conducted using publicly available data from the United Nations Programme on HIV/AIDS (UNAIDS) and Population Division, Demographic Health Surveys, and peer-review literature. National data from 70 countries, that had a UNAIDS estimate for the number of WLHIV nationally, were combined into country-level models. Models estimated the current number of infant HIV infections averted by contraception annually and potentially averted if unintended births to WLHIV were prevented. Estimates take into account pregnancy and live birth rates, contraceptive coverage, contraceptive method mix and failure rates, and HIV treatment coverage during pregnancy to prevent mother to child transmission. RESULTS: Contraception use among WLHIV prevents an estimated 43,559 new infant HIV infections annually across 70 countries. Countries with the largest number of infant infections averted by contraception included South Africa (9441), Nigeria (4195), Kenya (3508), Zimbabwe (2586), and India (2145). Preventing unintended births to WLHIV could avert an additional 43,768 new infant infections per year, with the greatest potential gains to be made in South Africa (12,036), Nigeria (2770), Uganda (2552), and the Democratic Republic of the Congo (2324). CONCLUSIONS: Contraception continues to play an integral role in global HIV prevention efforts in the era of increasing HIV treatment coverage, especially in sub-Saharan Africa. Broad contraceptive availability, increased contraceptive voluntarism and method mix are key components to preventing unintended births and ending new infant HIV infections worldwide. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-10570-w. |
format | Online Article Text |
id | pubmed-7977320 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-79773202021-03-22 The role of contraception in preventing HIV-positive births: global estimates and projections Sherwood, Jennifer Lankiewicz, Elise Roose-Snyder, Beirne Cooper, Bergen Jones, Austin Honermann, Brian BMC Public Health Research Article BACKGROUND: Meeting the contraceptive needs of women living with HIV (WLHIV) has primary health benefits for women, in addition to being a key element to prevent mother-to-child HIV transmission. This analysis will estimate the current number of infant HIV infections prevented by contraception in the era of increased HIV treatment coverage and; 2) model the additional HIV benefits of preventing unintended births to WLHIV. METHODS: Secondary data analysis was conducted using publicly available data from the United Nations Programme on HIV/AIDS (UNAIDS) and Population Division, Demographic Health Surveys, and peer-review literature. National data from 70 countries, that had a UNAIDS estimate for the number of WLHIV nationally, were combined into country-level models. Models estimated the current number of infant HIV infections averted by contraception annually and potentially averted if unintended births to WLHIV were prevented. Estimates take into account pregnancy and live birth rates, contraceptive coverage, contraceptive method mix and failure rates, and HIV treatment coverage during pregnancy to prevent mother to child transmission. RESULTS: Contraception use among WLHIV prevents an estimated 43,559 new infant HIV infections annually across 70 countries. Countries with the largest number of infant infections averted by contraception included South Africa (9441), Nigeria (4195), Kenya (3508), Zimbabwe (2586), and India (2145). Preventing unintended births to WLHIV could avert an additional 43,768 new infant infections per year, with the greatest potential gains to be made in South Africa (12,036), Nigeria (2770), Uganda (2552), and the Democratic Republic of the Congo (2324). CONCLUSIONS: Contraception continues to play an integral role in global HIV prevention efforts in the era of increasing HIV treatment coverage, especially in sub-Saharan Africa. Broad contraceptive availability, increased contraceptive voluntarism and method mix are key components to preventing unintended births and ending new infant HIV infections worldwide. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12889-021-10570-w. BioMed Central 2021-03-19 /pmc/articles/PMC7977320/ /pubmed/33740919 http://dx.doi.org/10.1186/s12889-021-10570-w Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Sherwood, Jennifer Lankiewicz, Elise Roose-Snyder, Beirne Cooper, Bergen Jones, Austin Honermann, Brian The role of contraception in preventing HIV-positive births: global estimates and projections |
title | The role of contraception in preventing HIV-positive births: global estimates and projections |
title_full | The role of contraception in preventing HIV-positive births: global estimates and projections |
title_fullStr | The role of contraception in preventing HIV-positive births: global estimates and projections |
title_full_unstemmed | The role of contraception in preventing HIV-positive births: global estimates and projections |
title_short | The role of contraception in preventing HIV-positive births: global estimates and projections |
title_sort | role of contraception in preventing hiv-positive births: global estimates and projections |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977320/ https://www.ncbi.nlm.nih.gov/pubmed/33740919 http://dx.doi.org/10.1186/s12889-021-10570-w |
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