Cargando…
Compensatory combination of mTOR and TrxR inhibitors to cause oxidative stress and regression of tumors
Background: Cancer is a leading cause of death worldwide. Extensive research over decades has led to the development of therapies that inhibit oncogenic signaling pathways. The mammalian target of rapamycin (mTOR) signaling pathway plays an important role in the development of many cancers. Several...
Autores principales: | Xia, Yiqun, Chen, Jundixia, Yu, Yun, Wu, Fengjiao, Shen, Xin, Qiu, Chenyu, Zhang, Tingting, Hong, Lin, Zheng, Peisen, Shao, Rongrong, Xu, Chenxin, Wu, Fang, Chen, Wei, Xie, Congying, Cui, Ri, Zou, Peng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977446/ https://www.ncbi.nlm.nih.gov/pubmed/33754064 http://dx.doi.org/10.7150/thno.52077 |
Ejemplares similares
-
Curcuminoid WZ35 synergize with cisplatin by inducing ROS production and inhibiting TrxR1 activity in gastric cancer cells
por: He, Wei, et al.
Publicado: (2019) -
To inhibit TrxR1 is to inactivate STAT3–Inhibition of TrxR1 enzymatic function by STAT3 small molecule inhibitors
por: Busker, Sander, et al.
Publicado: (2020) -
TIGAR knockdown radiosensitizes TrxR1-overexpressing glioma in vitro and in vivo via inhibiting Trx1 nuclear transport
por: Zhang, Yushuo, et al.
Publicado: (2017) -
Co-Targeting of BTK and TrxR as a Therapeutic Approach to the Treatment of Lymphoma
por: Wang, Sicong, et al.
Publicado: (2023) -
Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells
por: Wu, Peng, et al.
Publicado: (2020)