Intratumor heterogeneity of breast cancer detected by epialleles shows association with hypoxic microenvironment

Rationale: In breast cancer, high intratumor DNA methylation heterogeneity can lead to drug-resistant, metastasis and poor prognosis of tumors, which increases the complexity of cancer diagnosis and treatment. However, most studies are limited to average DNA methylation level of individual CpGs and...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yihan, Zhang, Yan, Huang, Yan, Chen, Chuangeng, Zhang, Xingda, Xing, Ying, Gu, Yue, Zhang, Mengyan, Cai, Li, Xu, Shouping, Sun, Baoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977462/
https://www.ncbi.nlm.nih.gov/pubmed/33754068
http://dx.doi.org/10.7150/thno.53737

Ejemplares similares

Ejemplares similares