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Dabigatran activates inflammation resolution by promoting fibrinogen-like protein 2 shedding and RvD5(n-3 DPA) production

Rationale: The interaction between coagulation and inflammation resolution remains elusive. We recently highlighted a link between fibrinogen-like protein 2 (Fgl2) and a specialized pro-resolving mediator (SPM)-n-3 docosapentaenoic acid-derived resolvin D5 (RvD5(n-3 DPA)) in sepsis. This study aimed...

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Detalles Bibliográficos
Autores principales: Lei, Juan, Zhou, Yu, Zhao, Huakan, Chen, Yu, Yan, Guifang, Wu, Lei, Xu, Yanquan, Zhang, Jiangang, Zhang, Xiao, Wang, Jingchun, Li, Dingshan, Li, Yongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977467/
https://www.ncbi.nlm.nih.gov/pubmed/33754059
http://dx.doi.org/10.7150/thno.50182