Cargando…

Hepatic miR-378 modulates serum cholesterol levels by regulating hepatic bile acid synthesis

Rationale: An improved understanding of thyroid hormone (TH) action on cholesterol metabolism will facilitate the identification of novel therapeutic targets for hypercholesterolemia. TH-regulated microRNAs (miRNAs) have been implicated in TH-controlled biological processes; however, whether and how...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Chao, Liu, Wei, Lu, Zhiqiang, Li, Yan, Liu, Shengnan, Tang, Zhili, Yan, Ying, Li, Zhiyang, Feng, Hua, Zhang, Duo, Liu, Yun, Fang, Zhong-Ze, Jiang, Changtao, Ding, Qiurong, Jiang, Jingjing, Ying, Hao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7977473/ https://www.ncbi.nlm.nih.gov/pubmed/33754066 http://dx.doi.org/10.7150/thno.53624

Ejemplares similares

Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism
por: Yan, Ying, et al.
Publicado: (2022)

Comparison of fresh and browning lotus roots (Nelumbo nucifera Gaertn.) on modulating cholesterol metabolism via decreasing hepatic cholesterol deposition and increasing fecal bile acid excretion
por: Li, Jingfang, et al.
Publicado: (2023)

miR-378b Regulates Insulin Sensitivity by Targeting Insulin Receptor and p110α in Alcohol-Induced Hepatic Steatosis
por: Li, Yuan-yuan, et al.
Publicado: (2020)

Ablation of gut microbiota alleviates obesity-induced hepatic steatosis and glucose intolerance by modulating bile acid metabolism in hamsters
por: Sun, Lulu, et al.
Publicado: (2019)

Cold-activated brown fat-derived extracellular vesicle-miR-378a-3p stimulates hepatic gluconeogenesis in male mice
por: Xu, Jinhong, et al.
Publicado: (2023)

Chemotherapy-elicited exosomal miR-378a-3p and miR-378d promote breast cancer stemness and chemoresistance via the activation of EZH2/STAT3 signaling
por: Yang, Qianxi, et al.
Publicado: (2021)

microRNA-378b regulates ethanol-induced hepatic steatosis by targeting CaMKK2 to mediate lipid metabolism
por: Wang, Ying-Zhao, et al.
Publicado: (2021)

Suppressed expression of miR-378 targeting gzmb in NK cells is required to control dengue virus infection
por: Liu, Shuyan, et al.
Publicado: (2016)

miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling
por: Peng, Jie, et al.
Publicado: (2021)

Dietary Betaine Addition Promotes Hepatic Cholesterol Synthesis, Bile Acid Conversion, and Export in Rats
por: Li, Sisi, et al.
Publicado: (2020)

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis
por: Wang, Yifeng, et al.
Publicado: (2020)

MiR‐378a‐3p as a putative biomarker for hepatocellular carcinoma diagnosis and prognosis: Computational screening with experimental validation
por: Qian, Fuliang, et al.
Publicado: (2021)

Negative Association of Plasma Levels of Vitamin D and miR-378 With Viral Load in Patients With Chronic Hepatitis B Infection
por: Mohamadkhani, Ashraf, et al.
Publicado: (2015)

Hypomethylation of MIR‐378 5’‐flanking region predicts poor survival in young patients with myelodysplastic syndrome
por: Wu, De‐hong, et al.
Publicado: (2019)

STUDIES ON GALL BLADDER FUNCTION : VIII. THE FATE OF BILE PIGMENT AND CHOLESTEROL IN HEPATIC BILE SUBJECTED TO GALL BLADDER ACTIVITY
por: Riegel, Cecilia, et al.
Publicado: (1932)

Dietary pulp from Fructus Schisandra Chinensis supplementation reduces serum/hepatic lipid and hepatic glucose levels in mice fed a normal or high cholesterol/bile salt diet
por: Sun, Nan, et al.
Publicado: (2014)

Depicting the Implication of miR-378a in Cancers
por: Qin, Yuelan, et al.
Publicado: (2022)

Caffeic acid dimethyl ether alleviates alcohol-induced hepatic steatosis via microRNA-378b-mediated CaMKK2-AMPK pathway
por: Lu, Jun, et al.
Publicado: (2022)

PM378. A reduced risk of severe hepatic outcome with paliperidone exposure in schizophrenia patients with viral hepatitis: a population-based retrospective cohort study
por: Chang, Chun-Hung, et al.
Publicado: (2016)

Effects of tegaserod on bile composition and hepatic secretion in Richardson ground squirrels on an enriched cholesterol diet
por: Mathison, Ronald, et al.
Publicado: (2006)

Inulin Supplementation Disturbs Hepatic Cholesterol and Bile Acid Metabolism Independent from Housing Temperature
por: Pauly, Mira J., et al.
Publicado: (2020)

Identification of serum miR-378 and miR-575 as diagnostic indicators and predicting surgical prognosis in human epilepsy
por: Li, Xiuxiu, et al.
Publicado: (2022)

Functional SNPs of INCENP Affect Semen Quality by Alternative Splicing Mode and Binding Affinity with the Target Bta-miR-378 in Chinese Holstein Bulls
por: Liu, Juan, et al.
Publicado: (2016)

Running Head: Heat Affects Cholesterol and Bile Acid Alterations in Cholesterol and Bile Acids Metabolism in Large White Pigs during Short-Term Heat Exposure
por: Fang, Wei, et al.
Publicado: (2020)

MiR-378a suppresses tenogenic differentiation and tendon repair by targeting at TGF-β2
por: Liu, Yang, et al.
Publicado: (2019)

Serum exosomal miR‐378 upregulation is associated with poor prognosis in non–small‐cell lung cancer patients
por: Zhang, Yan, et al.
Publicado: (2020)

Circulating miR-378 and miR-451 in serum are potential biomarkers for renal cell carcinoma
por: Redova, Martina, et al.
Publicado: (2012)

Aberrant Brain Bile Acid Signaling and Cholesterol Accumulation: A New Look at Mechanisms in Hepatic Encephalopathy
por: Jayakumar, Arumugam R., et al.
Publicado: (2018)

Exosomes from miRNA-378-modified adipose-derived stem cells prevent glucocorticoid-induced osteonecrosis of the femoral head by enhancing angiogenesis and osteogenesis via targeting miR-378 negatively regulated suppressor of fused (Sufu)
por: Nan, Kai, et al.
Publicado: (2021)

Vine tea extract ameliorated acute liver injury by inhibiting hepatic autophagy and reversing abnormal bile acid metabolism
por: Li, Ying, et al.
Publicado: (2023)

Hepatic bile acids and bile acid-related gene expression in pregnant and lactating rats
por: Zhu, Qiong N., et al.
Publicado: (2013)

microRNA and thyroid hormone signaling in cardiac and skeletal muscle
por: Zhang, Duo, et al.
Publicado: (2017)

MiR-378a-5p Regulates Proliferation and Migration in Vascular Smooth Muscle Cell by Targeting CDK1
por: Liu, Shaoyan, et al.
Publicado: (2019)

The Role of miR-378a in Metabolism, Angiogenesis, and Muscle Biology
por: Krist, Bart, et al.
Publicado: (2015)

Lack of miR-378 attenuates muscular dystrophy in mdx mice
por: Podkalicka, Paulina, et al.
Publicado: (2020)

Loss of lncRNA-SNHG7 Promotes the Suppression of Hepatic Stellate Cell Activation via miR-378a-3p and DVL2
por: Yu, Fujun, et al.
Publicado: (2019)

Loss of lncRNA-SNHG7 Promotes the Suppression of Hepatic Stellate Cell Activation via miR-378a-3p and DVL2
por: Yu, Fujun, et al.
Publicado: (2020)

MicroRNA-378 limits activation of hepatic stellate cells and liver fibrosis by suppressing Gli3 expression
por: Hyun, Jeongeun, et al.
Publicado: (2016)

Circulating miR-21, miR-378, and miR-940 increase in response to an acute exhaustive exercise in chronic heart failure patients
por: Xu, Tianzhao, et al.
Publicado: (2016)

Corrigendum: MiR-378a-5p Regulates Proliferation and Migration in Vascular Smooth Muscle Cell by Targeting CDK1
por: Liu, Shaoyan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_m3scfva834n0uja2fthukik963