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Hydroxychloroquine is associated with lower platelet activity and improved vascular health in systemic lupus erythematosus

OBJECTIVE: Hydroxychloroquine (HCQ) is a mainstay of therapy in the treatment of SLE. The effect of HCQ on platelets and vascular health is uncertain. We investigated the relationship between HCQ use and dose with platelet activity, platelet transcriptomics and vascular health in patients with SLE....

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Detalles Bibliográficos
Autores principales: Cornwell, MacIntosh Grant, Luttrell-Williams, Elliot S, Golpanian, Michael, El Bannoudi, Hanane, Myndzar, Khrystyna, Izmirly, Peter, Belmont, H Michael, Katz, Stuart, Smilowitz, Nathaniel R, Engel, Alexis, Clancy, Robert, Ruggles, Kelly, Buyon, Jill P, Berger, Jeffrey S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978255/
https://www.ncbi.nlm.nih.gov/pubmed/33737451
http://dx.doi.org/10.1136/lupus-2021-000475