Deficiency of telomere-associated repressor activator protein 1 precipitates cardiac aging in mice via p53/PPARα signaling

Background: Telomere shortening and dysfunction may cause metabolic disorders, tissue damage and age-dependent pathologies. However, little is known about the association of telomere-associated protein Rap1 with mitochondrial energy metabolism and cardiac aging. Methods: Echocardiography was perform...

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Detalles Bibliográficos
Autores principales: Cai, Yin, Liu, Hao, Song, Erfei, Wang, Lin, Xu, Jindong, He, Yi, Zhang, Dengwen, Zhang, Liyan, Cheng, Kenneth King-yip, Jin, Leigang, Wu, Min, Liu, Shiming, Qi, Dake, Zhang, Liangqing, Lopaschuk, Gary D., Wang, Sheng, Xu, Aimin, Xia, Zhengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978321/
https://www.ncbi.nlm.nih.gov/pubmed/33754023
http://dx.doi.org/10.7150/thno.51739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978321/
https://www.ncbi.nlm.nih.gov/pubmed/33754023
http://dx.doi.org/10.7150/thno.51739

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