Single-cell transcriptome analysis of the heterogeneous effects of differential expression of tumor PD-L1 on responding TCR-T cells

Rationale: TCR-T cell therapy plays a critical role in the treatment of malignant cancers. However, it is unclear how TCR-T cells are affected by PD-L1 molecule in the tumor environment. We performed an in-depth evaluation on how differential expressions of tumor PD-L1 can affect the functionality o...

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Detalles Bibliográficos
Autores principales: Ding, Renpeng, Liu, Shang, Wang, Shanshan, Chen, Huanyi, Wang, Fei, Xu, Qumiao, Zhu, Linnan, Dong, Xuan, Gu, Ying, Zhang, Xiuqing, Chao, Cheng-Chi, Gao, Qianqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7978322/
https://www.ncbi.nlm.nih.gov/pubmed/33754038
http://dx.doi.org/10.7150/thno.55075

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