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Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study
During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979149/ https://www.ncbi.nlm.nih.gov/pubmed/33739987 http://dx.doi.org/10.1371/journal.pone.0246314 |
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author | Zaferani Arani, Hamid Dehghan Manshadi, Giti Atashi, Hesam Adin Rezaei Nejad, Aida Ghorani, Seyyed Mojtaba Abolghasemi, Soheila Bahrani, Maryam Khaledian, Homayoon Bozorg Savodji, Pantea Hoseinian, Mohammad Kazemzade Bejandi, Atefe Abolghasemi, Shahla |
author_facet | Zaferani Arani, Hamid Dehghan Manshadi, Giti Atashi, Hesam Adin Rezaei Nejad, Aida Ghorani, Seyyed Mojtaba Abolghasemi, Soheila Bahrani, Maryam Khaledian, Homayoon Bozorg Savodji, Pantea Hoseinian, Mohammad Kazemzade Bejandi, Atefe Abolghasemi, Shahla |
author_sort | Zaferani Arani, Hamid |
collection | PubMed |
description | During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries facing the second wave of coronavirus, due to the lack of appropriate public restrictions because of economic problems the country is facing. The clinical and demographic characteristics of severe cases and non-severe cases of Coronavirus Disease (COVID-19) in 192 patients in Tehran, Iran, between June 16 and July 11, 2020, were investigated. The patients were divided into severe cases (n = 82) and non-severe cases (n = 110). Demographic and clinical characteristics were compared between the two study clusters. The mean age was 54.6 ± 17.2 years, and the most common presenting symptom was persistent cough (81.8%) and fever (79.7%). The logistic regression model revealed that age, BMI, and affected family members were statistically associated with severity. Patients with complicated conditions of disorders faced more hospitalization days and medical care than the average statistical data. As the coronavirus spike in the case and death reports from June 2020, we observed the rise in the incidence of severe cases, where 42.7% (82/192) of cases have resulted in severe conditions. Our findings also suggested that the effect of IFB (Betamethasone) was more valid than the other alternative drugs such as LPV/r and IVIg. |
format | Online Article Text |
id | pubmed-7979149 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-79791492021-03-31 Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study Zaferani Arani, Hamid Dehghan Manshadi, Giti Atashi, Hesam Adin Rezaei Nejad, Aida Ghorani, Seyyed Mojtaba Abolghasemi, Soheila Bahrani, Maryam Khaledian, Homayoon Bozorg Savodji, Pantea Hoseinian, Mohammad Kazemzade Bejandi, Atefe Abolghasemi, Shahla PLoS One Research Article During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries facing the second wave of coronavirus, due to the lack of appropriate public restrictions because of economic problems the country is facing. The clinical and demographic characteristics of severe cases and non-severe cases of Coronavirus Disease (COVID-19) in 192 patients in Tehran, Iran, between June 16 and July 11, 2020, were investigated. The patients were divided into severe cases (n = 82) and non-severe cases (n = 110). Demographic and clinical characteristics were compared between the two study clusters. The mean age was 54.6 ± 17.2 years, and the most common presenting symptom was persistent cough (81.8%) and fever (79.7%). The logistic regression model revealed that age, BMI, and affected family members were statistically associated with severity. Patients with complicated conditions of disorders faced more hospitalization days and medical care than the average statistical data. As the coronavirus spike in the case and death reports from June 2020, we observed the rise in the incidence of severe cases, where 42.7% (82/192) of cases have resulted in severe conditions. Our findings also suggested that the effect of IFB (Betamethasone) was more valid than the other alternative drugs such as LPV/r and IVIg. Public Library of Science 2021-03-19 /pmc/articles/PMC7979149/ /pubmed/33739987 http://dx.doi.org/10.1371/journal.pone.0246314 Text en © 2021 Zaferani Arani et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Zaferani Arani, Hamid Dehghan Manshadi, Giti Atashi, Hesam Adin Rezaei Nejad, Aida Ghorani, Seyyed Mojtaba Abolghasemi, Soheila Bahrani, Maryam Khaledian, Homayoon Bozorg Savodji, Pantea Hoseinian, Mohammad Kazemzade Bejandi, Atefe Abolghasemi, Shahla Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study |
title | Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study |
title_full | Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study |
title_fullStr | Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study |
title_full_unstemmed | Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study |
title_short | Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study |
title_sort | understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in tehran, iran: a retrospective study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979149/ https://www.ncbi.nlm.nih.gov/pubmed/33739987 http://dx.doi.org/10.1371/journal.pone.0246314 |
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