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Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study

During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries...

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Autores principales: Zaferani Arani, Hamid, Dehghan Manshadi, Giti, Atashi, Hesam Adin, Rezaei Nejad, Aida, Ghorani, Seyyed Mojtaba, Abolghasemi, Soheila, Bahrani, Maryam, Khaledian, Homayoon, Bozorg Savodji, Pantea, Hoseinian, Mohammad, Kazemzade Bejandi, Atefe, Abolghasemi, Shahla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979149/
https://www.ncbi.nlm.nih.gov/pubmed/33739987
http://dx.doi.org/10.1371/journal.pone.0246314
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author Zaferani Arani, Hamid
Dehghan Manshadi, Giti
Atashi, Hesam Adin
Rezaei Nejad, Aida
Ghorani, Seyyed Mojtaba
Abolghasemi, Soheila
Bahrani, Maryam
Khaledian, Homayoon
Bozorg Savodji, Pantea
Hoseinian, Mohammad
Kazemzade Bejandi, Atefe
Abolghasemi, Shahla
author_facet Zaferani Arani, Hamid
Dehghan Manshadi, Giti
Atashi, Hesam Adin
Rezaei Nejad, Aida
Ghorani, Seyyed Mojtaba
Abolghasemi, Soheila
Bahrani, Maryam
Khaledian, Homayoon
Bozorg Savodji, Pantea
Hoseinian, Mohammad
Kazemzade Bejandi, Atefe
Abolghasemi, Shahla
author_sort Zaferani Arani, Hamid
collection PubMed
description During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries facing the second wave of coronavirus, due to the lack of appropriate public restrictions because of economic problems the country is facing. The clinical and demographic characteristics of severe cases and non-severe cases of Coronavirus Disease (COVID-19) in 192 patients in Tehran, Iran, between June 16 and July 11, 2020, were investigated. The patients were divided into severe cases (n = 82) and non-severe cases (n = 110). Demographic and clinical characteristics were compared between the two study clusters. The mean age was 54.6 ± 17.2 years, and the most common presenting symptom was persistent cough (81.8%) and fever (79.7%). The logistic regression model revealed that age, BMI, and affected family members were statistically associated with severity. Patients with complicated conditions of disorders faced more hospitalization days and medical care than the average statistical data. As the coronavirus spike in the case and death reports from June 2020, we observed the rise in the incidence of severe cases, where 42.7% (82/192) of cases have resulted in severe conditions. Our findings also suggested that the effect of IFB (Betamethasone) was more valid than the other alternative drugs such as LPV/r and IVIg.
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spelling pubmed-79791492021-03-31 Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study Zaferani Arani, Hamid Dehghan Manshadi, Giti Atashi, Hesam Adin Rezaei Nejad, Aida Ghorani, Seyyed Mojtaba Abolghasemi, Soheila Bahrani, Maryam Khaledian, Homayoon Bozorg Savodji, Pantea Hoseinian, Mohammad Kazemzade Bejandi, Atefe Abolghasemi, Shahla PLoS One Research Article During the last months of the coronavirus pandemic, with all those public restrictions and health interventions, the transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) appears now to have been raised in some countries around the world. Iran was one of those first countries facing the second wave of coronavirus, due to the lack of appropriate public restrictions because of economic problems the country is facing. The clinical and demographic characteristics of severe cases and non-severe cases of Coronavirus Disease (COVID-19) in 192 patients in Tehran, Iran, between June 16 and July 11, 2020, were investigated. The patients were divided into severe cases (n = 82) and non-severe cases (n = 110). Demographic and clinical characteristics were compared between the two study clusters. The mean age was 54.6 ± 17.2 years, and the most common presenting symptom was persistent cough (81.8%) and fever (79.7%). The logistic regression model revealed that age, BMI, and affected family members were statistically associated with severity. Patients with complicated conditions of disorders faced more hospitalization days and medical care than the average statistical data. As the coronavirus spike in the case and death reports from June 2020, we observed the rise in the incidence of severe cases, where 42.7% (82/192) of cases have resulted in severe conditions. Our findings also suggested that the effect of IFB (Betamethasone) was more valid than the other alternative drugs such as LPV/r and IVIg. Public Library of Science 2021-03-19 /pmc/articles/PMC7979149/ /pubmed/33739987 http://dx.doi.org/10.1371/journal.pone.0246314 Text en © 2021 Zaferani Arani et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zaferani Arani, Hamid
Dehghan Manshadi, Giti
Atashi, Hesam Adin
Rezaei Nejad, Aida
Ghorani, Seyyed Mojtaba
Abolghasemi, Soheila
Bahrani, Maryam
Khaledian, Homayoon
Bozorg Savodji, Pantea
Hoseinian, Mohammad
Kazemzade Bejandi, Atefe
Abolghasemi, Shahla
Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study
title Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study
title_full Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study
title_fullStr Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study
title_full_unstemmed Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study
title_short Understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in Tehran, Iran: A retrospective study
title_sort understanding the clinical and demographic characteristics of second coronavirus spike in 192 patients in tehran, iran: a retrospective study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979149/
https://www.ncbi.nlm.nih.gov/pubmed/33739987
http://dx.doi.org/10.1371/journal.pone.0246314
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