Cargando…

Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain

Post COVID-19 vaccine development, nations are now getting ready to face another challenge: how to effectively distribute vaccines amongst the masses to quickly achieve herd immunity against the infection. According to some experts, herd immunity for COVID-19 can be achieved by inoculating 67% of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Sinha, Priyank, Kumar, Sameer, Chandra, Charu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979275/
https://www.ncbi.nlm.nih.gov/pubmed/33776195
http://dx.doi.org/10.1016/j.ejor.2021.03.030
_version_ 1783667247962652672
author Sinha, Priyank
Kumar, Sameer
Chandra, Charu
author_facet Sinha, Priyank
Kumar, Sameer
Chandra, Charu
author_sort Sinha, Priyank
collection PubMed
description Post COVID-19 vaccine development, nations are now getting ready to face another challenge: how to effectively distribute vaccines amongst the masses to quickly achieve herd immunity against the infection. According to some experts, herd immunity for COVID-19 can be achieved by inoculating 67% of the population. India may find it difficult to achieve this service level target, owing to several infrastructural deficiencies in its vaccine supply chain. Effect of these deficiencies is to cause frequent lead time disruptions. In this context, we develop a novel modelling approach to identify few nodes, which require additional inventory allocations (strategic inventory reserves) to ensure minimum service level (67%) under the possibility of lead time disruptions. Later, through an illustrative case study on distribution of Japanese Encephalitis vaccine, we identify conditions under which strategic inventory reserve policy cannot be practically implemented to meet service level targets. Nodes fulfilling these conditions are termed as critical nodes and must be overhauled structurally to make the implementation of strategic inventory policy practically viable again. Structural overhauling may entail installation of better cold storage facilities, purchasing more quality transport vans, improving reliability of transport network, and skills of cold storage manager by training. Ideally, conditions for identifying critical nodes for COVID-19 vaccine distribution must be derived separately by substituting COVID-19 specific parametric values in our model. In the absence of the required data for COVID-19 scenario, JE specific criteria can be used heuristically to identify critical nodes and structurally overhaul them later for efficiently achieving service level targets.
format Online
Article
Text
id pubmed-7979275
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-79792752021-03-23 Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain Sinha, Priyank Kumar, Sameer Chandra, Charu Eur J Oper Res Article Post COVID-19 vaccine development, nations are now getting ready to face another challenge: how to effectively distribute vaccines amongst the masses to quickly achieve herd immunity against the infection. According to some experts, herd immunity for COVID-19 can be achieved by inoculating 67% of the population. India may find it difficult to achieve this service level target, owing to several infrastructural deficiencies in its vaccine supply chain. Effect of these deficiencies is to cause frequent lead time disruptions. In this context, we develop a novel modelling approach to identify few nodes, which require additional inventory allocations (strategic inventory reserves) to ensure minimum service level (67%) under the possibility of lead time disruptions. Later, through an illustrative case study on distribution of Japanese Encephalitis vaccine, we identify conditions under which strategic inventory reserve policy cannot be practically implemented to meet service level targets. Nodes fulfilling these conditions are termed as critical nodes and must be overhauled structurally to make the implementation of strategic inventory policy practically viable again. Structural overhauling may entail installation of better cold storage facilities, purchasing more quality transport vans, improving reliability of transport network, and skills of cold storage manager by training. Ideally, conditions for identifying critical nodes for COVID-19 vaccine distribution must be derived separately by substituting COVID-19 specific parametric values in our model. In the absence of the required data for COVID-19 scenario, JE specific criteria can be used heuristically to identify critical nodes and structurally overhaul them later for efficiently achieving service level targets. Elsevier B.V. 2023-01-01 2021-03-20 /pmc/articles/PMC7979275/ /pubmed/33776195 http://dx.doi.org/10.1016/j.ejor.2021.03.030 Text en © 2021 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Sinha, Priyank
Kumar, Sameer
Chandra, Charu
Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain
title Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain
title_full Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain
title_fullStr Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain
title_full_unstemmed Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain
title_short Strategies for ensuring required service level for COVID-19 herd immunity in Indian vaccine supply chain
title_sort strategies for ensuring required service level for covid-19 herd immunity in indian vaccine supply chain
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979275/
https://www.ncbi.nlm.nih.gov/pubmed/33776195
http://dx.doi.org/10.1016/j.ejor.2021.03.030
work_keys_str_mv AT sinhapriyank strategiesforensuringrequiredservicelevelforcovid19herdimmunityinindianvaccinesupplychain
AT kumarsameer strategiesforensuringrequiredservicelevelforcovid19herdimmunityinindianvaccinesupplychain
AT chandracharu strategiesforensuringrequiredservicelevelforcovid19herdimmunityinindianvaccinesupplychain