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Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series

Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases o...

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Detalles Bibliográficos
Autores principales: Nucera, Eleonora, Urbani, Sara, Buonomo, Alessandro, De Pasquale, Tiziana, Rizzi, Angela, Aruanno, Arianna, Pucci, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979346/
https://www.ncbi.nlm.nih.gov/pubmed/33758514
http://dx.doi.org/10.2147/JAA.S295748
Descripción
Sumario:Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.