Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series

Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases o...

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Autores principales: Nucera, Eleonora, Urbani, Sara, Buonomo, Alessandro, De Pasquale, Tiziana, Rizzi, Angela, Aruanno, Arianna, Pucci, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979346/
https://www.ncbi.nlm.nih.gov/pubmed/33758514
http://dx.doi.org/10.2147/JAA.S295748
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author Nucera, Eleonora
Urbani, Sara
Buonomo, Alessandro
De Pasquale, Tiziana
Rizzi, Angela
Aruanno, Arianna
Pucci, Stefano
author_facet Nucera, Eleonora
Urbani, Sara
Buonomo, Alessandro
De Pasquale, Tiziana
Rizzi, Angela
Aruanno, Arianna
Pucci, Stefano
author_sort Nucera, Eleonora
collection PubMed
description Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism.
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spelling pubmed-79793462021-03-22 Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series Nucera, Eleonora Urbani, Sara Buonomo, Alessandro De Pasquale, Tiziana Rizzi, Angela Aruanno, Arianna Pucci, Stefano J Asthma Allergy Case Series Gadolinium-based contrast agents (GBCAs) are considered to be safe, although sometimes patients report a hypersensitivity reaction when undergoing magnetic resonance imaging (MRI). The mechanisms of these reactions and of the sensitization to GBCAs are still largely unknown. We describe four cases of patients who experienced immediate adverse reactions to GBCAs with a demonstrated cutaneous hypersensitivity suggesting an IgE-mediated mechanism. Dove 2021-03-15 /pmc/articles/PMC7979346/ /pubmed/33758514 http://dx.doi.org/10.2147/JAA.S295748 Text en © 2021 Nucera et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Series
Nucera, Eleonora
Urbani, Sara
Buonomo, Alessandro
De Pasquale, Tiziana
Rizzi, Angela
Aruanno, Arianna
Pucci, Stefano
Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
title Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
title_full Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
title_fullStr Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
title_full_unstemmed Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
title_short Gadolinium-Based Contrast Agents Hypersensitivity: A Case Series
title_sort gadolinium-based contrast agents hypersensitivity: a case series
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979346/
https://www.ncbi.nlm.nih.gov/pubmed/33758514
http://dx.doi.org/10.2147/JAA.S295748
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