A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis

Leptin Receptor(+) (LepR(+)) stromal cells in adult bone marrow are a critical source of growth factors, including Stem Cell Factor (SCF), for the maintenance of hematopoietic stem cells (HSCs) and early restricted progenitors(1–6). LepR(+) cells are heterogeneous, including skeletal stem cells, ost...

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Detalles Bibliográficos
Autores principales: Shen, Bo, Tasdogan, Alpaslan, Ubellacker, Jessalyn M., Zhang, Jingzhu, Nosyreva, Elena D, Du, Liming, Murphy, Malea M., Hu, Shuiqing, Yi, Yating, Kara, Nergis, Liu, Xin, Guela, Shay, Jia, Yuemeng, Ramesh, Vijayashree, Embree, Claire, Mitchell, Evann C., Zhao, Yunduo C., Ju, Lining A., Hu, Zhao, Crane, Genevieve M., Zhao, Zhiyu, Syeda, Ruhma, Morrison, Sean J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979521/
https://www.ncbi.nlm.nih.gov/pubmed/33627868
http://dx.doi.org/10.1038/s41586-021-03298-5

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