Cargando…
The deubiquitinase (DUB) USP13 promotes Mcl-1 stabilisation in cervical cancer
Protein ubiquitination is a critical regulator of cellular homeostasis. Aberrations in the addition or removal of ubiquitin can result in the development of cancer and key components of the ubiquitination machinery serve as oncogenes or tumour suppressors. An emerging target in the development of ca...
Autores principales: | Morgan, Ethan L., Patterson, Molly R., Barba-Moreno, Diego, Scarth, James A., Wilson, Adam, Macdonald, Andrew |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979541/ https://www.ncbi.nlm.nih.gov/pubmed/33627786 http://dx.doi.org/10.1038/s41388-021-01679-8 |
Ejemplares similares
-
Deubiquitinase USP13 dictates MCL1 stability and sensitivity to BH3 mimetic inhibitors
por: Zhang, Shengzhe, et al.
Publicado: (2018) -
E6-mediated activation of JNK drives EGFR signalling to promote proliferation and viral oncoprotein expression in cervical cancer
por: Morgan, Ethan L., et al.
Publicado: (2020) -
The emerging role of Deubiquitinases (DUBs) in parasites: A foresight review
por: Kumar, Prakash, et al.
Publicado: (2022) -
Roles and Mechanisms of Deubiquitinases (DUBs) in Breast Cancer Progression and Targeted Drug Discovery
por: Li, Sixuan, et al.
Publicado: (2021) -
Interaction of Deubiquitinase 2A-DUB/MYSM1 with DNA Repair and Replication Factors
por: Kroeger, Carsten, et al.
Publicado: (2020)