Synergistic Inhibition of Drug-Resistant Colon Cancer Growth with PI3K/mTOR Dual Inhibitor BEZ235 and Nano-Emulsioned Paclitaxel via Reducing Multidrug Resistance and Promoting Apoptosis

BACKGROUND: Colon cancer is a top lethal cancer in man and women worldwide and drug resistance is the major cause of cancer-related death. Combinational therapy and drug delivery with nanoparticles have been shown to effectively overcome drug resistance in many cancers. We previously reported that n...

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Detalles Bibliográficos
Autores principales: Hu, Yali, Zhang, Kunpeng, Zhu, Xingyao, Zheng, Xiuyan, Wang, Chao, Niu, Xiao, Jiang, Teng, Ji, Xinhua, Zhao, Weilin, Pang, Lijuan, Qi, Yan, Li, Feng, Li, Li, Xu, Zhiping, Gu, Wenyi, Zou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979685/
https://www.ncbi.nlm.nih.gov/pubmed/33758505
http://dx.doi.org/10.2147/IJN.S290731

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