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Randomized, crossover clinical efficacy trial in humans and mice on tear secretion promotion and lacrimal gland protection by molecular hydrogen
The incidence of dry eye disease is increasing worldwide because of the aging population and increasing use of information technology. Dry eye disease manifests as tear-layer instability and inflammation caused by osmotic hypersensitization in tear fluids; however, to our knowledge, no agent that tr...
Autores principales: | Kubota, Miyuki, Kawashima, Motoko, Inoue, Sachiko, Imada, Toshihiro, Nakamura, Shigeru, Kubota, Shunsuke, Watanabe, Mitsuhiro, Takemura, Ryo, Tsubota, Kazuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979688/ https://www.ncbi.nlm.nih.gov/pubmed/33742060 http://dx.doi.org/10.1038/s41598-021-85895-y |
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