β-catenin-promoted cholesterol metabolism protects against cellular senescence in naked mole-rat cells

The naked mole-rat (NMR; Heterocephalus glaber) exhibits cancer resistance and an exceptionally long lifespan of approximately 30 years, but the mechanism(s) underlying increased longevity in NMRs remains unclear. In the present study, we report unique mechanisms underlying cholesterol metabolism in...

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Detalles Bibliográficos
Autores principales: Chee, Woei-Yaw, Kurahashi, Yuriko, Kim, Junhyeong, Miura, Kyoko, Okuzaki, Daisuke, Ishitani, Tohru, Kajiwara, Kentaro, Nada, Shigeyuki, Okano, Hideyuki, Okada, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979689/
https://www.ncbi.nlm.nih.gov/pubmed/33742113
http://dx.doi.org/10.1038/s42003-021-01879-8

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