Cargando…

Immune complex-induced apoptosis and concurrent immune complex clearance are anti-inflammatory neutrophil functions

Persistent neutrophilic inflammation drives host damage in autoimmune diseases that are characterized by abundant immune complexes. Insoluble immune complexes (iICs) potently activate pro-inflammatory neutrophil effector functions. We and others have shown that iICs also promote resolution of inflam...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karmakar, Utsa, Chu, Julia Y., Sundaram, Kruthika, Astier, Anne L., Garside, Hannah, Hansen, Carsten G., Dransfield, Ian, Vermeren, Sonja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979711/ https://www.ncbi.nlm.nih.gov/pubmed/33741905 http://dx.doi.org/10.1038/s41419-021-03528-8

Ejemplares similares

Crosstalk between B cells and neutrophils in rheumatoid arthritis
por: Karmakar, Utsa, et al.
Publicado: (2021)

Non-canonical PI3K-Cdc42-Pak-Mek-Erk Signaling Promotes Immune-Complex-Induced Apoptosis in Human Neutrophils
por: Chu, Julia Y., et al.
Publicado: (2016)

The 5-Phosphatase SHIP2 Promotes Neutrophil Chemotaxis and Recruitment
por: Michael, Melina, et al.
Publicado: (2021)

Editorial: Neutrophil Functions in Host Immunity, Inflammation and Tissue Repair
por: Vermeren, Sonja, et al.
Publicado: (2021)

Clearance of immune complexes formed in normal and leukaemic rats.
por: Shepherd, P. S., et al.
Publicado: (1980)

Anti-Inflammatory Neutrophil Functions in the Resolution of Inflammation and Tissue Repair
por: Loh, Waywen, et al.
Publicado: (2022)

Clearance of circulating DNA-anti-DNA immune complexes in mice
Publicado: (1982)

Effects of Glucocorticoids on Apoptosis and Clearance of Apoptotic Cells
por: McColl, Aisleen, et al.
Publicado: (2007)

HoxB8 neutrophils replicate Fcγ receptor and integrin‐induced neutrophil signaling and functions
por: Chu, Julia Y., et al.
Publicado: (2018)

A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites
por: McCormick, Barry, et al.
Publicado: (2019)

Neutrophil Extracellular Traps in Autoimmunity and Allergy: Immune Complexes at Work
por: Granger, Vanessa, et al.
Publicado: (2019)

Immune complex-mediated neutrophil activation in patients with polymyalgia rheumatica
por: Michailidou, Despina, et al.
Publicado: (2022)

PTPN22 Is a Critical Regulator of Fcγ Receptor–Mediated Neutrophil Activation
por: Vermeren, Sonja, et al.
Publicado: (2016)

Blockade of clearance of immune complexes by an anti-F(cγ) receptor monoclonal antibody
por: Clarkson, SB, et al.
Publicado: (1986)

The inhibitory receptor FcγRII reduces joint inflammation in immune complex arthritis not only by inhibition of activatory FcγR but also by efficient clearance of immune complexes
por: van Lent, PL, et al.
Publicado: (2003)

Clearance of circulating IgA immune complexes is mediated by a specific receptor on Kupffer cells in mice
Publicado: (1984)

Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance
por: Sugimoto, Michelle Amantéa, et al.
Publicado: (2016)

Immune complex-stimulated neutrophil LTB4 production is dependent on beta 2 integrins
Publicado: (1993)

Chemokinetic accumulation of human neutrophils on immune complex-coated substrata: analysis at a boundary
Publicado: (1984)

Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen
por: Revathikumar, Priya, et al.
Publicado: (2018)

Correction: Microsomal prostaglandin E synthase-1 gene deletion impairs neuro-immune circuitry of the cholinergic anti-inflammatory pathway in endotoxaemic mouse spleen
por: Revathikumar, Priya, et al.
Publicado: (2018)

Immune clearance of highly pathogenic SIV infection
por: Hansen, Scott G., et al.
Publicado: (2013)

Serum bile acids in liver cirrhosis promote neutrophil dysfunction
por: Balazs, Irina, et al.
Publicado: (2022)

The Immune Response in Measles: Virus Control, Clearance and Protective Immunity
por: Griffin, Diane E.
Publicado: (2016)

Reduced Neutrophil Apoptosis in Diabetic Mice during Staphylococcal Infection Leads to Prolonged Tnfα Production and Reduced Neutrophil Clearance
por: Hanses, Frank, et al.
Publicado: (2011)

The impact of immunogenicity on therapeutic antibody pharmacokinetics: A preclinical evaluation of the effect of immune complex formation and antibody effector function on clearance
por: Opolka-Hoffmann, Eugenia, et al.
Publicado: (2021)

The “Phagocytic Synapse” and Clearance of Apoptotic Cells
por: Barth, Nicole D., et al.
Publicado: (2017)

TLR7/8 activation in neutrophils impairs immune complex phagocytosis through shedding of FcgRIIA
por: Lood, Christian, et al.
Publicado: (2017)

Peptide inhibition of neutrophil-mediated injury after in vivo challenge with supernatant of Pseudomonas aeruginosa and immune-complexes
por: Enos, Adrianne, et al.
Publicado: (2021)

Immune complex–driven neutrophil activation and BAFF release: a link to B cell responses in SLE
por: Wang, Ting, et al.
Publicado: (2022)

Clearing the complexity: immune complexes and their treatment in lupus nephritis
por: Toong, Catherine, et al.
Publicado: (2011)

How complex are intracellular immune receptor signaling complexes?
por: Bonardi, Vera, et al.
Publicado: (2012)

Immune Thrombosis: Exploring the Significance of Immune Complexes and NETosis
por: Perdomo, José, et al.
Publicado: (2023)

ARF: Connecting senescence and innate immunity for clearance
por: Kearney, Alper Y., et al.
Publicado: (2015)

Lymphatic Clearance of Immune Cells in Cardiovascular Disease
por: Ravaud, Christophe, et al.
Publicado: (2021)

Vitamin D/CD46 Crosstalk in Human T Cells in Multiple Sclerosis
por: Killick, Justin, et al.
Publicado: (2020)

The EGFR/ErbB inhibitor neratinib modifies the neutrophil phosphoproteome and promotes apoptosis and clearance by airway macrophages
por: Herman, Kimberly D., et al.
Publicado: (2022)

Inhibition of Immune Complex Complement Activation and Neutrophil Extracellular Trap Formation by Peptide Inhibitor of Complement C1
por: Hair, Pamela S., et al.
Publicado: (2018)

Regulation of Apoptotic Cell Clearance During Resolution of Inflammation
por: Arienti, Simone, et al.
Publicado: (2019)

A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis
por: Barth, Nicole D., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7ousghm8c1nc7icr077ug11j60