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Oncolytic adeno-immunotherapy modulates the immune system enabling CAR T-cells to cure pancreatic tumors

High expression levels of human epidermal growth factor receptor 2 (HER2) have been associated with poor prognosis in patients with pancreatic adenocarcinoma (PDAC). However, HER2-targeting immunotherapies have been unsuccessful to date. Here we increase the breadth, potency, and duration of anti-PD...

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Detalles Bibliográficos
Autores principales:	Rosewell Shaw, Amanda, Porter, Caroline E., Yip, Tiffany, Mah, Way-Champ, McKenna, Mary K., Dysthe, Matthew, Jung, Youngrock, Parihar, Robin, Brenner, Malcolm K., Suzuki, Masataka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979740/ https://www.ncbi.nlm.nih.gov/pubmed/33742099 http://dx.doi.org/10.1038/s42003-021-01914-8

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