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Exploration of natural red-shifted rhodopsins using a machine learning-based Bayesian experimental design
Microbial rhodopsins are photoreceptive membrane proteins, which are used as molecular tools in optogenetics. Here, a machine learning (ML)-based experimental design method is introduced for screening rhodopsins that are likely to be red-shifted from representative rhodopsins in the same subfamily....
Autores principales: | Inoue, Keiichi, Karasuyama, Masayuki, Nakamura, Ryoko, Konno, Masae, Yamada, Daichi, Mannen, Kentaro, Nagata, Takashi, Inatsu, Yu, Yawo, Hiromu, Yura, Kei, Béjà, Oded, Kandori, Hideki, Takeuchi, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979833/ https://www.ncbi.nlm.nih.gov/pubmed/33742139 http://dx.doi.org/10.1038/s42003-021-01878-9 |
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