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Il-10 signaling reduces survival in mouse models of synucleinopathy

Parkinson’s disease (PD) and related synucleinopathies are characterized by chronic neuroinflammation leading to the premise that anti-inflammatory therapies could ameliorate synucleinopathy and associated sequelae. To test this idea, we used recombinant adeno-associated viruses (AAV) to express the...

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Detalles Bibliográficos
Autores principales:	Cockey, Samuel G., McFarland, Karen N., Koller, Emily J., Brooks, Mieu M. T., Gonzalez De La Cruz, Elsa, Cruz, Pedro E., Ceballos-Diaz, Carolina, Rosario, Awilda M., Levites, Yona R., Borchelt, David R., Golde, Todd E., Giasson, Benoit I., Chakrabarty, Paramita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979923/ https://www.ncbi.nlm.nih.gov/pubmed/33741985 http://dx.doi.org/10.1038/s41531-021-00169-8

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