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Stress undermines reward-guided cognitive performance through synaptic depression in the lateral habenula
Weighing alternatives during reward pursuit is a vital cognitive computation that, when disrupted by stress, yields aspects of neuropsychiatric disorders. To examine the neural mechanisms underlying these phenomena, we employed a behavioral task in which mice were confronted by a reward and its omis...
Autores principales: | Nuno-Perez, Alvaro, Trusel, Massimo, Lalive, Arnaud L., Congiu, Mauro, Gastaldo, Denise, Tchenio, Anna, Lecca, Salvatore, Soiza-Reilly, Mariano, Bagni, Claudia, Mameli, Manuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980092/ https://www.ncbi.nlm.nih.gov/pubmed/33535028 http://dx.doi.org/10.1016/j.neuron.2021.01.008 |
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