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Structure of the catalytic core of the Integrator complex

The Integrator is a specialized 3′ end-processing complex involved in cleavage and transcription termination of a subset of nascent RNA polymerase II transcripts, including small nuclear RNAs (snRNAs). We provide evidence of the modular nature of the Integrator complex by biochemically characterizin...

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Detalles Bibliográficos
Autores principales: Pfleiderer, Moritz M., Galej, Wojciech P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980224/
https://www.ncbi.nlm.nih.gov/pubmed/33548203
http://dx.doi.org/10.1016/j.molcel.2021.01.005