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In this issue, Wang et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.201911114) describe a phenomenon in which neuromuscular junction synapse elimination triggers myelination of terminal motor axon branches. They propose a mechanism initiated by synaptic pruning that depends on synaptic activ...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Rockefeller University Press
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980256/ https://www.ncbi.nlm.nih.gov/pubmed/33734302 http://dx.doi.org/10.1083/jcb.202102030 |
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author | Haddix, Seth G. Rasband, Matthew N. |
author_facet | Haddix, Seth G. Rasband, Matthew N. |
author_sort | Haddix, Seth G. |
collection | PubMed |
description | In this issue, Wang et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.201911114) describe a phenomenon in which neuromuscular junction synapse elimination triggers myelination of terminal motor axon branches. They propose a mechanism initiated by synaptic pruning that depends on synaptic activity, cytoskeletal maturation, and the associated anterograde transport of trophic factors including Neuregulin 1-III. |
format | Online Article Text |
id | pubmed-7980256 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-79802562021-10-05 Lose it to use it Haddix, Seth G. Rasband, Matthew N. J Cell Biol Spotlight In this issue, Wang et al. (2021. J. Cell Biol. https://doi.org/10.1083/jcb.201911114) describe a phenomenon in which neuromuscular junction synapse elimination triggers myelination of terminal motor axon branches. They propose a mechanism initiated by synaptic pruning that depends on synaptic activity, cytoskeletal maturation, and the associated anterograde transport of trophic factors including Neuregulin 1-III. Rockefeller University Press 2021-03-18 /pmc/articles/PMC7980256/ /pubmed/33734302 http://dx.doi.org/10.1083/jcb.202102030 Text en © 2021 Haddix and Rasband http://www.rupress.org/terms/https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Spotlight Haddix, Seth G. Rasband, Matthew N. Lose it to use it |
title | Lose it to use it |
title_full | Lose it to use it |
title_fullStr | Lose it to use it |
title_full_unstemmed | Lose it to use it |
title_short | Lose it to use it |
title_sort | lose it to use it |
topic | Spotlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980256/ https://www.ncbi.nlm.nih.gov/pubmed/33734302 http://dx.doi.org/10.1083/jcb.202102030 |
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