A specific RIP3(+) subpopulation of microglia promotes retinopathy through a hypoxia-triggered necroptotic mechanism

Retinal neovascularization is a leading cause of severe visual loss in humans, and molecular mechanisms of microglial activation-driven angiogenesis remain unknown. Using single-cell RNA sequencing, we identified a subpopulation of microglia named sMG2, which highly expressed necroptosis-related gen...

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Detalles Bibliográficos
Autores principales: He, Chang, Liu, Yan, Huang, Zijing, Yang, Ziqi, Zhou, Tian, Liu, Sheng, Hao, Zhaozhe, Wang, Jing, Feng, Qiumin, Liu, Yizhi, Cao, Yihai, Liu, Xialin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980367/
https://www.ncbi.nlm.nih.gov/pubmed/33836603
http://dx.doi.org/10.1073/pnas.2023290118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980367/
https://www.ncbi.nlm.nih.gov/pubmed/33836603
http://dx.doi.org/10.1073/pnas.2023290118

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