Cargando…
Genetic deletion of Nox4 enhances cancerogen-induced formation of solid tumors
Reactive oxygen species (ROS) can cause cellular damage and promote cancer development. Besides such harmful consequences of overproduction of ROS, all cells utilize ROS for signaling purposes and stabilization of cell homeostasis. In particular, the latter is supported by the NADPH oxidase 4 (Nox4)...
Autores principales: | Helfinger, Valeska, Freiherr von Gall, Florian, Henke, Nina, Kunze, Michael M., Schmid, Tobias, Rezende, Flavia, Heidler, Juliana, Wittig, Ilka, Radeke, Heinfried H., Marschall, Viola, Anderson, Karen, Shah, Ajay M., Fulda, Simone, Brüne, Bernhard, Brandes, Ralf P., Schröder, Katrin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980388/ https://www.ncbi.nlm.nih.gov/pubmed/33836590 http://dx.doi.org/10.1073/pnas.2020152118 |
Ejemplares similares
-
BIAM switch assay coupled to mass spectrometry identifies novel redox targets of NADPH oxidase 4
por: Löwe, Oliver, et al.
Publicado: (2019) -
NoxO1 Controls Proliferation of Colon Epithelial Cells
por: Moll, Franziska, et al.
Publicado: (2018) -
Studies on the Cancerogenic Azo and Related Compounds
por: Kinosita, Riojun
Publicado: (1940) -
The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice
por: Rezende, Flávia, et al.
Publicado: (2017) -
The NADPH Oxidase Nox4 Controls Macrophage Polarization in an NFκB-Dependent Manner
por: Helfinger, V., et al.
Publicado: (2019)