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Screening for gene expression fluctuations reveals latency-promoting agents of HIV

Upon treatment removal, spontaneous reactivation of latently infected T cells remains a major barrier toward curing HIV. Therapies that reactivate and clear the latent reservoir are only partially effective, while latency-promoting agents (LPAs) used to suppress reactivation and stabilize latency ar...

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Detalles Bibliográficos
Autores principales: Lu, Yiyang, Bohn-Wippert, Kathrin, Pazerunas, Patrick J., Moy, Jennifer M., Singh, Harpal, Dar, Roy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980449/
https://www.ncbi.nlm.nih.gov/pubmed/33836565
http://dx.doi.org/10.1073/pnas.2012191118