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Screening for gene expression fluctuations reveals latency-promoting agents of HIV
Upon treatment removal, spontaneous reactivation of latently infected T cells remains a major barrier toward curing HIV. Therapies that reactivate and clear the latent reservoir are only partially effective, while latency-promoting agents (LPAs) used to suppress reactivation and stabilize latency ar...
Autores principales: | Lu, Yiyang, Bohn-Wippert, Kathrin, Pazerunas, Patrick J., Moy, Jennifer M., Singh, Harpal, Dar, Roy D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980449/ https://www.ncbi.nlm.nih.gov/pubmed/33836565 http://dx.doi.org/10.1073/pnas.2012191118 |
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