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Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review

INTRODUCTION: Multiple studies suggest that SARS-CoV-2 infection is associated with a pro-thrombotic state and thrombotic events have been recorded in several organs and systems. We report a patient with no respiratory symptoms, presented with abdominal pain and an extensive splenic infarction after...

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Autores principales: Castro, Gustavo Rodrigues Alves, Collaço, Iwan Augusto, Dal Bosco, Caroline L. Balcewicz, Corrêa, Gustavo Gusso, Dal Bosco, Giovana Balcewicz, Corrêa, Giovana Luiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980490/
https://www.ncbi.nlm.nih.gov/pubmed/33777695
http://dx.doi.org/10.1016/j.idcr.2021.e01062
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author Castro, Gustavo Rodrigues Alves
Collaço, Iwan Augusto
Dal Bosco, Caroline L. Balcewicz
Corrêa, Gustavo Gusso
Dal Bosco, Giovana Balcewicz
Corrêa, Giovana Luiza
author_facet Castro, Gustavo Rodrigues Alves
Collaço, Iwan Augusto
Dal Bosco, Caroline L. Balcewicz
Corrêa, Gustavo Gusso
Dal Bosco, Giovana Balcewicz
Corrêa, Giovana Luiza
author_sort Castro, Gustavo Rodrigues Alves
collection PubMed
description INTRODUCTION: Multiple studies suggest that SARS-CoV-2 infection is associated with a pro-thrombotic state and thrombotic events have been recorded in several organs and systems. We report a patient with no respiratory symptoms, presented with abdominal pain and an extensive splenic infarction after COVID-19. CASE REPORT: A 67 year-old man was admitted to the emergency department with a moderate, dull, left-sided abdominal pain. The patient denied respiratory symptoms but referred contact with family members positive for COVID-19. He tested positive for COVID-19 and had increased D-dimer levels. Imaging studies revealed splenic infarcts and ground-glass opacities in bilateral pulmonary bases. He was treated with full-dose anticoagulation and was discharged home on oral Rivaroxaban. DISCUSSION: Although rare in the literature, cases of acute abdomen in COVID-19 patients associated with vascular infarctions have increased. Coagulopathy may be present even without clinical respiratory manifestations of the disease. Patients meeting disseminated intravascular coagulation criteria or with markedly elevated D-dimer may benefit from anticoagulant therapy. CONCLUSION: Clinicians should suspect of abdominal visceral infarctions in COVID-19 patients presented with acute abdominal pain, despite the absence of respiratory symptoms.
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spelling pubmed-79804902021-03-23 Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review Castro, Gustavo Rodrigues Alves Collaço, Iwan Augusto Dal Bosco, Caroline L. Balcewicz Corrêa, Gustavo Gusso Dal Bosco, Giovana Balcewicz Corrêa, Giovana Luiza IDCases Case Report INTRODUCTION: Multiple studies suggest that SARS-CoV-2 infection is associated with a pro-thrombotic state and thrombotic events have been recorded in several organs and systems. We report a patient with no respiratory symptoms, presented with abdominal pain and an extensive splenic infarction after COVID-19. CASE REPORT: A 67 year-old man was admitted to the emergency department with a moderate, dull, left-sided abdominal pain. The patient denied respiratory symptoms but referred contact with family members positive for COVID-19. He tested positive for COVID-19 and had increased D-dimer levels. Imaging studies revealed splenic infarcts and ground-glass opacities in bilateral pulmonary bases. He was treated with full-dose anticoagulation and was discharged home on oral Rivaroxaban. DISCUSSION: Although rare in the literature, cases of acute abdomen in COVID-19 patients associated with vascular infarctions have increased. Coagulopathy may be present even without clinical respiratory manifestations of the disease. Patients meeting disseminated intravascular coagulation criteria or with markedly elevated D-dimer may benefit from anticoagulant therapy. CONCLUSION: Clinicians should suspect of abdominal visceral infarctions in COVID-19 patients presented with acute abdominal pain, despite the absence of respiratory symptoms. Elsevier 2021-03-20 /pmc/articles/PMC7980490/ /pubmed/33777695 http://dx.doi.org/10.1016/j.idcr.2021.e01062 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Castro, Gustavo Rodrigues Alves
Collaço, Iwan Augusto
Dal Bosco, Caroline L. Balcewicz
Corrêa, Gustavo Gusso
Dal Bosco, Giovana Balcewicz
Corrêa, Giovana Luiza
Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review
title Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review
title_full Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review
title_fullStr Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review
title_full_unstemmed Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review
title_short Splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: A case report and literature review
title_sort splenic infarction as a complication of covid-19 in a patient without respiratory symptoms: a case report and literature review
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980490/
https://www.ncbi.nlm.nih.gov/pubmed/33777695
http://dx.doi.org/10.1016/j.idcr.2021.e01062
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