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The Zinc Finger Protein Zbtb18 Represses Expression of Class I Phosphatidylinositol 3-Kinase Subunits and Inhibits Plasma Cell Differentiation
The PI3K pathway plays a key role in B cell activation and is important for the differentiation of Ab producing plasma cells (PCs). Although much is known about the molecular mechanisms that modulate PI3K signaling in B cells, the transcriptional regulation of PI3K expression is poorly understood. I...
Autores principales: | Xie, Bin, Khoyratty, Tariq E., Abu-Shah, Enas, F. Cespedes, Pablo, MacLean, Andrew J., Pirgova, Gabriela, Hu, Zhiyuan, Ahmed, Ahmed A., Dustin, Michael L., Udalova, Irina A., Arnon, Tal I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7980533/ https://www.ncbi.nlm.nih.gov/pubmed/33608456 http://dx.doi.org/10.4049/jimmunol.2000367 |
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